Removing the filtering of amino acid changes with '+' as not relevant… #10487
Conversation
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
rmadupuri
approved these changes
Dec 12, 2023
|
Looks good! Thanks for catching that! |
|
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.
This suggestion is invalid because no changes were made to the code.
Suggestions cannot be applied while the pull request is closed.
Suggestions cannot be applied while viewing a subset of changes.
Only one suggestion per line can be applied in a batch.
Add this suggestion to a batch that can be applied as a single commit.
Applying suggestions on deleted lines is not supported.
You must change the existing code in this line in order to create a valid suggestion.
Outdated suggestions cannot be applied.
This suggestion has been applied or marked resolved.
Suggestions cannot be applied from pending reviews.
Suggestions cannot be applied on multi-line comments.
Suggestions cannot be applied while the pull request is queued to merge.
Suggestion cannot be applied right now. Please check back later.
… anymore
This PR addresses an issue identified in the current variant representation guidelines. According to Q1 under Q&A on HGVS nomenclature rules, the use of the '+' sign was previously a method to represent multiple changes together. This format is not recommended anymore, and it restricts the loading of 5' intronic splicing variants, such as c.357+1G>A.