Mutational signatures generated for studies (do not merge) #1784
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MatthijsPon
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SRodenburg
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ritikakundra
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ritikakundra
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Closing, as we are now adding published signature data in #1824 |
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Preview PR (not for actual merging)
Mutational signatures extracted from cBioPortal MAF files.
These mutational signature profiles are purely for demonstration and this is not a good practice for generating mutational signatures, as MAF files are curated and do not reflect a full mutational spectrum.
Studies with mutational signatures:
Smoking history vs SBS4 (Smoking) -
nsclc_tcga_broad_2016UV signatures high in contribution and significant (determined with 100 permutations) -
skcm_tcga_pan_can_atlas_2018This is the datahub preview of RFC64.
Related front-end PR cBioPortal/cbioportal-frontend#4540 containing the front-end implementation.
Related back-end PR cBioPortal/datahub-study-curation-tools#48 containing the script used for mutational-signature extraction and metafile generation