lumpy filter: error while loading shared libraries: libcrypto.so.1.0.0

[Madelinehazel]

This is an error that came up when running smoove. It looks like this is because we only have openssl version 1.1 in the anaconda installation on the CHEO-RI space (/storage/modules/anaconda/2020.11/lib/), when we need openssl version 1.0 to run smoove. See related issue, and this issue.
In the hpf anaconda installation, openssl version 1.0 is present as a symlink pointing to openssl version 1.1. It is unclear if this was a temporary fix.

[DanielOsmond]

I've had the same issue when trying to run Smoove after installing with conda, with an error message relating to not finding libcrypto.so.1.0.0. Has there been a resolution please?

[Madelinehazel]

Hi Daniel, sorry for the delay in response. I had to add bcftools to the conda environment (- bcftools ==1.13), and then after creating the environment with snakemake, create a symlink libcrypto.so.1.0.0 pointing to libcrypto.so.1.1- not a nice solution, admittedly!

[DanielOsmond]

Hi Madeline, thanks for the response. I got around it in the end by just creating a symlink in my own libraries doing the same - seems to do the job!