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Finnish/Estonian 21J lineage (20%) with S:411S (part of ORF1a:261N branch) #273

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corneliusroemer opened this issue Oct 19, 2021 · 2 comments
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@corneliusroemer
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New lineage proposal
by @corneliusroemer

Description
Sub-lineage of #268 (21J with ORF1a:261N) need to read with this comment #268 (comment)
Earliest sequence: May to July 2021 in Finland
Most recent sequence: Current
Countries circulating: ~20% in Finland and Estonia

Lineage deriving from Delta 21J branch with ORF1a:261N with extra mut S:411S

image

https://nextstrain.org/groups/neherlab/ncov/finland?branchLabel=aa&c=gt-S_411&gmin=15&label=spike_mutations:I95T&m=div

image

image

https://cov-spectrum-develop-git-lapis-and-refactoring-cov-spectrum.vercel.app/explore/World/AllSamples/Past6M/variants?aaMutations=S%3A411S%2CORF1a%3A261N&pangoLineage=B.1.617.2*

Country Total Variant Sequences First seq. found at Last seq. found at
Finland 935 2021-25 2021-37
Germany 3 2021-27 2021-37
Estonia 178 2021-28 2021-37
United States 5 2021-29 2021-37
Sweden 661 2021-29 2021-39
Denmark 7 2021-30 2021-33
United Kingdom 5 2021-30 2021-40
New Zealand 1 2021-30 2021-30
Norway 11 2021-31 2021-34
Switzerland 7 2021-33 2021-38
France 12 2021-34 2021-38
Iceland 1 2021-34 2021-34
Slovenia 1 2021-34 2021-34
Czechia 3 2021-34 2021-35
Turkey 1 2021-36 2021-36
Lithuania 2 2021-37 2021-38

AY.N.x (where N is chosen together with #267 and #268)

@FedeGueli
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The parental lineage has been designated AY.122 in #320 .
Pls @corneliusroemer evaluate if closing this or keeoing it monitored

chrisruis added a commit that referenced this issue Dec 10, 2021
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Thanks @corneliusroemer This clade is a sublineage of AY.122 and increased as a proportion of total AY.122 in both Finland and Estonia. It may now be declining but is still responsible for ~30% of AY.122 sequences in these countries in the most recent weeks with data. We've therefore added this as AY.122.2 in v1.2.109 to start on the branch with G22793T (S:A411S)

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