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Proposal of new sub-lineage of AY.3 for Peru with principal mutation in Spike: T259I, A942T #312

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IrisSilvaINS opened this issue Nov 9, 2021 · 3 comments
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@IrisSilvaINS
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IrisSilvaINS commented Nov 9, 2021

Proposal for a new sub lineage of AY.3 with principal mutation in Spike: T259I, A942T in Peruvian genomes by Group of Genomic Surveillance INS-PERU

Description
Sub-lineage of: Potentially new sub lineage of AY.3 (S: T259I, A942T mutations in of Peruvian genomes)
Earliest sequence: hCoV-19/Peru/JUN-INS-6934/2021(2021/09/12, Peru)
Most recent sequence: hCoV-19/Peru/LAM-INS-8260/2021(2021/10/12, Peru)

Countries circulating: Peru (23)

The lineage of AY.3 was designed #121 (carried mutation: ORF1a: I3731V), the genomes of new sub lineage carried two additional mutation in Spike: T259I, A942T. This potentially AY.3.X is spread pronominally in Lima, capital of Peru.

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See here for further details:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_1d473_a80600.json?tl=pango_lineage

Share of all sequences in Peru
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Genomes:

New_sub_lineage.txt

@corneliusroemer
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Even 12 days later, it's still only 23 sequences, which is a bit too few to warrant a designation for now covSpectrum

@corneliusroemer corneliusroemer added the monitor currently too small, watch for future developments label Nov 22, 2021
@OrsonMM
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OrsonMM commented Nov 25, 2021

IRIS_2
IRIS_1

@chrisruis
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Thanks @IrisSilvaINS It looks like this clade has continued to circulate so we've added this as AY.3.2 in v1.2.111 to start on the branch with C22338T (S:T259I)

@chrisruis chrisruis added this to the AY.3.2 milestone Dec 13, 2021
@chrisruis chrisruis added designated and removed monitor currently too small, watch for future developments labels Dec 13, 2021
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