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17 changes: 3 additions & 14 deletions exercises/practice/hamming/.docs/instructions.md
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# Instructions

Calculate the Hamming Distance between two DNA strands.
Calculate the Hamming distance between two DNA strands.

Your body is made up of cells that contain DNA.
Those cells regularly wear out and need replacing, which they achieve by dividing into daughter cells.
In fact, the average human body experiences about 10 quadrillion cell divisions in a lifetime!

When cells divide, their DNA replicates too.
Sometimes during this process mistakes happen and single pieces of DNA get encoded with the incorrect information.
If we compare two strands of DNA and count the differences between them we can see how many mistakes occurred.
This is known as the "Hamming Distance".

We read DNA using the letters C,A,G and T.
We read DNA using the letters C, A, G and T.
Two strands might look like this:

GAGCCTACTAACGGGAT
CATCGTAATGACGGCCT
^ ^ ^ ^ ^ ^^

They have 7 differences, and therefore the Hamming Distance is 7.

The Hamming Distance is useful for lots of things in science, not just biology, so it's a nice phrase to be familiar with :)
They have 7 differences, and therefore the Hamming distance is 7.

## Implementation notes

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12 changes: 12 additions & 0 deletions exercises/practice/hamming/.docs/introduction.md
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# Introduction

Your body is made up of cells that contain DNA.
Those cells regularly wear out and need replacing, which they achieve by dividing into daughter cells.
In fact, the average human body experiences about 10 quadrillion cell divisions in a lifetime!

When cells divide, their DNA replicates too.
Sometimes during this process mistakes happen and single pieces of DNA get encoded with the incorrect information.
If we compare two strands of DNA and count the differences between them, we can see how many mistakes occurred.
This is known as the "Hamming distance".

The Hamming distance is useful in many areas of science, not just biology, so it's a nice phrase to be familiar with :)
2 changes: 1 addition & 1 deletion exercises/practice/hamming/.meta/config.json
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Expand Up @@ -17,7 +17,7 @@
".meta/example.vim"
]
},
"blurb": "Calculate the Hamming difference between two DNA strands.",
"blurb": "Calculate the Hamming distance between two DNA strands.",
"source": "The Calculating Point Mutations problem at Rosalind",
"source_url": "https://rosalind.info/problems/hamm/"
}
3 changes: 2 additions & 1 deletion exercises/practice/luhn/.docs/instructions.md
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Expand Up @@ -22,7 +22,8 @@ The first step of the Luhn algorithm is to double every second digit, starting f
We will be doubling

```text
4_3_ 3_9_ 0_4_ 6_6_
4539 3195 0343 6467
↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ (double these)
```

If doubling the number results in a number greater than 9 then subtract 9 from the product.
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8 changes: 4 additions & 4 deletions exercises/practice/protein-translation/.docs/instructions.md
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Translate RNA sequences into proteins.

RNA can be broken into three nucleotide sequences called codons, and then translated to a polypeptide like so:
RNA can be broken into three-nucleotide sequences called codons, and then translated to a protein like so:

RNA: `"AUGUUUUCU"` => translates to

Codons: `"AUG", "UUU", "UCU"`
=> which become a polypeptide with the following sequence =>
=> which become a protein with the following sequence =>

Protein: `"Methionine", "Phenylalanine", "Serine"`

Expand All @@ -27,9 +27,9 @@ Protein: `"Methionine", "Phenylalanine", "Serine"`

Note the stop codon `"UAA"` terminates the translation and the final methionine is not translated into the protein sequence.

Below are the codons and resulting Amino Acids needed for the exercise.
Below are the codons and resulting amino acids needed for the exercise.

| Codon | Protein |
| Codon | Amino Acid |
| :----------------- | :------------ |
| AUG | Methionine |
| UUU, UUC | Phenylalanine |
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6 changes: 3 additions & 3 deletions exercises/practice/rna-transcription/.docs/instructions.md
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# Instructions

Your task is determine the RNA complement of a given DNA sequence.
Your task is to determine the RNA complement of a given DNA sequence.

Both DNA and RNA strands are a sequence of nucleotides.

The four nucleotides found in DNA are adenine (**A**), cytosine (**C**), guanine (**G**) and thymine (**T**).
The four nucleotides found in DNA are adenine (**A**), cytosine (**C**), guanine (**G**), and thymine (**T**).

The four nucleotides found in RNA are adenine (**A**), cytosine (**C**), guanine (**G**) and uracil (**U**).
The four nucleotides found in RNA are adenine (**A**), cytosine (**C**), guanine (**G**), and uracil (**U**).

Given a DNA strand, its transcribed RNA strand is formed by replacing each nucleotide with its complement:

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31 changes: 17 additions & 14 deletions exercises/practice/space-age/.docs/instructions.md
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# Instructions

Given an age in seconds, calculate how old someone would be on:
Given an age in seconds, calculate how old someone would be on a planet in our Solar System.

- Mercury: orbital period 0.2408467 Earth years
- Venus: orbital period 0.61519726 Earth years
- Earth: orbital period 1.0 Earth years, 365.25 Earth days, or 31557600 seconds
- Mars: orbital period 1.8808158 Earth years
- Jupiter: orbital period 11.862615 Earth years
- Saturn: orbital period 29.447498 Earth years
- Uranus: orbital period 84.016846 Earth years
- Neptune: orbital period 164.79132 Earth years
One Earth year equals 365.25 Earth days, or 31,557,600 seconds.
If you were told someone was 1,000,000,000 seconds old, their age would be 31.69 Earth-years.

So if you were told someone were 1,000,000,000 seconds old, you should
be able to say that they're 31.69 Earth-years old.
For the other planets, you have to account for their orbital period in Earth Years:

If you're wondering why Pluto didn't make the cut, go watch [this YouTube video][pluto-video].
| Planet | Orbital period in Earth Years |
| ------- | ----------------------------- |
| Mercury | 0.2408467 |
| Venus | 0.61519726 |
| Earth | 1.0 |
| Mars | 1.8808158 |
| Jupiter | 11.862615 |
| Saturn | 29.447498 |
| Uranus | 84.016846 |
| Neptune | 164.79132 |

Note: The actual length of one complete orbit of the Earth around the sun is closer to 365.256 days (1 sidereal year).
~~~~exercism/note
The actual length of one complete orbit of the Earth around the sun is closer to 365.256 days (1 sidereal year).
The Gregorian calendar has, on average, 365.2425 days.
While not entirely accurate, 365.25 is the value used in this exercise.
See [Year on Wikipedia][year] for more ways to measure a year.
[pluto-video]: https://www.youtube.com/watch?v=Z_2gbGXzFbs
[year]: https://en.wikipedia.org/wiki/Year#Summary
~~~~
20 changes: 20 additions & 0 deletions exercises/practice/space-age/.docs/introduction.md
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# Introduction

The year is 2525 and you've just embarked on a journey to visit all planets in the Solar System (Mercury, Venus, Earth, Mars, Jupiter, Saturn, Uranus and Neptune).
The first stop is Mercury, where customs require you to fill out a form (bureaucracy is apparently _not_ Earth-specific).
As you hand over the form to the customs officer, they scrutinize it and frown.
"Do you _really_ expect me to believe you're just 50 years old?
You must be closer to 200 years old!"

Amused, you wait for the customs officer to start laughing, but they appear to be dead serious.
You realize that you've entered your age in _Earth years_, but the officer expected it in _Mercury years_!
As Mercury's orbital period around the sun is significantly shorter than Earth, you're actually a lot older in Mercury years.
After some quick calculations, you're able to provide your age in Mercury Years.
The customs officer smiles, satisfied, and waves you through.
You make a mental note to pre-calculate your planet-specific age _before_ future customs checks, to avoid such mix-ups.

~~~~exercism/note
If you're wondering why Pluto didn't make the cut, go watch [this YouTube video][pluto-video].
[pluto-video]: https://www.youtube.com/watch?v=Z_2gbGXzFbs
~~~~
17 changes: 11 additions & 6 deletions exercises/practice/square-root/.docs/instructions.md
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# Instructions

Given a natural radicand, return its square root.
Your task is to calculate the square root of a given number.

Note that the term "radicand" refers to the number for which the root is to be determined.
That is, it is the number under the root symbol.
- Try to avoid using the pre-existing math libraries of your language.
- As input you'll be given a positive whole number, i.e. 1, 2, 3, 4…
- You are only required to handle cases where the result is a positive whole number.

Check out the Wikipedia pages on [square root][square-root] and [methods of computing square roots][computing-square-roots].
Some potential approaches:

Recall also that natural numbers are positive real whole numbers (i.e. 1, 2, 3 and up).
- Linear or binary search for a number that gives the input number when squared.
- Successive approximation using Newton's or Heron's method.
- Calculating one digit at a time or one bit at a time.

[square-root]: https://en.wikipedia.org/wiki/Square_root
You can check out the Wikipedia pages on [integer square root][integer-square-root] and [methods of computing square roots][computing-square-roots] to help with choosing a method of calculation.

[integer-square-root]: https://en.wikipedia.org/wiki/Integer_square_root
[computing-square-roots]: https://en.wikipedia.org/wiki/Methods_of_computing_square_roots
10 changes: 10 additions & 0 deletions exercises/practice/square-root/.docs/introduction.md
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# Introduction

We are launching a deep space exploration rocket and we need a way to make sure the navigation system stays on target.

As the first step in our calculation, we take a target number and find its square root (that is, the number that when multiplied by itself equals the target number).

The journey will be very long.
To make the batteries last as long as possible, we had to make our rocket's onboard computer very power efficient.
Unfortunately that means that we can't rely on fancy math libraries and functions, as they use more power.
Instead we want to implement our own square root calculation.
4 changes: 2 additions & 2 deletions exercises/practice/sublist/.docs/instructions.md
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Expand Up @@ -8,8 +8,8 @@ Given any two lists `A` and `B`, determine if:
- None of the above is true, thus lists `A` and `B` are unequal

Specifically, list `A` is equal to list `B` if both lists have the same values in the same order.
List `A` is a superlist of `B` if `A` contains a sub-sequence of values equal to `B`.
List `A` is a sublist of `B` if `B` contains a sub-sequence of values equal to `A`.
List `A` is a superlist of `B` if `A` contains a contiguous sub-sequence of values equal to `B`.
List `A` is a sublist of `B` if `B` contains a contiguous sub-sequence of values equal to `A`.

Examples:

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2 changes: 1 addition & 1 deletion exercises/practice/yacht/.meta/config.json
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]
},
"blurb": "Score a single throw of dice in the game Yacht.",
"source": "James Kilfiger, using wikipedia",
"source": "James Kilfiger, using Wikipedia",
"source_url": "https://en.wikipedia.org/wiki/Yacht_(dice_game)"
}

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