Simulations for "A note on the amount of information borrowed from external data in hybrid controlled trials with time-to-event outcomes" by Segal and Tan.

Contents

• enee_sims_exp.R: Script for running exponential simulations
• enee_sims_weib.R: Script for running Weibull simulations
• enee_functions.R: Functions for estimating the generalized solution and generating trial data.
• enee_parameters.R: Sets simulation parameters used in enee_sims_exp.R and enee_sims_weib.R

Instructions for reproducing results

To reproduce the simulation results in the paper, run enee_sims_exp.R and enee_sims_weib.R.

References

Segal, B. D., Tan, W. K. (2020). A note on the amount of information borrowed from external data in hybrid controlled trials with time-to-event outcomes. https://arxiv.org/abs/2010.00433.