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Merge pull request #29385 from geneontology/histone-reader
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created new terms fixes #29384
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@pgaudet
pgaudet authored Dec 6, 2024
2 parents 2276d07 + 210d902 commit 0c9a7ba
Showing 1 changed file with 126 additions and 8 deletions.
134 changes: 126 additions & 8 deletions src/ontology/go-edit.obo
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Expand Up @@ -359730,7 +359730,7 @@ namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 27." [GOC:dph, PMID:23948251]
synonym: "H3-K27me3 modified histone binding" NARROW []
synonym: "H3K27me3 modified histone binding" NARROW []
is_a: GO:0140566 ! histone reader activity
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27427" xsd:anyURI

Expand Down Expand Up @@ -364160,7 +364160,7 @@ name: H3K9me3 histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 9." [PMID:30110338]
synonym: "H3K9me3 modified histone binding" NARROW []
is_a: GO:0140566 ! histone reader activity
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27427" xsd:anyURI

Expand Down Expand Up @@ -450180,9 +450180,9 @@ namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 4." [PMID:15647753, PMID:23318260]
synonym: "H3-K4me3 modified histone binding" NARROW []
synonym: "H3K4me3 modified histone binding" NARROW []
is_a: GO:0140566 ! histone reader activity
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29337" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-11-29T14:13:16Z

Expand All @@ -450193,7 +450193,7 @@ namespace: molecular_function
def: "A histone reader that recognizes a histone H3 trimethylated at lysine 36." [PMID:15489290, PMID:16364921]
synonym: "H3-K36me3 modified histone binding" NARROW []
synonym: "H3K36me3 modified histone binding" NARROW []
is_a: GO:0140566 ! histone reader activity
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29337" xsd:anyURI
created_by: pg
Expand All @@ -450206,7 +450206,7 @@ namespace: molecular_function
def: "A histone reader that recognizes a histone H3 serotonylated at glutamine 5." [PMID:34144982]
synonym: "H3Q5-serotonin histone reader activity" EXACT []
synonym: "H3Q5-serotonin modified histone binding" NARROW []
is_a: GO:0140566 ! histone reader activity
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29337" xsd:anyURI
created_by: pg
Expand All @@ -450218,12 +450218,23 @@ name: H4K20me2 histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 dimethylated at lysine 20." [PMID:22150589]
synonym: "H4K20me2 modified histone binding" NARROW []
is_a: GO:0140566 ! histone reader activity
is_a: GO:0140008 ! H4 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24912" xsd:anyURI
created_by: pg
creation_date: 2024-11-29T15:16:39Z

[Term]
id: GO:0140006
name: H3 histone reader activity
namespace: molecular_function
def: "A histone reader that specifically binds either to an unmodified histone H3 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
is_a: GO:0140566 ! histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27427" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T13:03:19Z

[Term]
id: GO:0140007
name: KICSTOR complex
Expand All @@ -450234,6 +450245,17 @@ relationship: capable_of_part_of GO:1903432 ! regulation of TORC1 signaling
created_by: pg
creation_date: 2017-03-10T12:47:30Z

[Term]
id: GO:0140008
name: H4 histone reader activity
namespace: molecular_function
def: "A histone reader that specifically binds either to an unmodified histone H4 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
is_a: GO:0140566 ! histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T13:09:47Z

[Term]
id: GO:0140009
name: L-aspartate import across plasma membrane
Expand All @@ -450258,6 +450280,30 @@ relationship: part_of GO:0070777 ! D-aspartate transmembrane transport
created_by: pg
creation_date: 2017-03-13T11:15:15Z

[Term]
id: GO:0140011
name: H4K12ac histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 acetylated at lysine 12." [PMID:14731392]
synonym: "H4K12ac modified histone binding" NARROW []
is_a: GO:0140008 ! H4 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:08:12Z

[Term]
id: GO:0140012
name: H4K5ac histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 acetylated at lysine 5." [PMID:18406326, PMID:20709061]
synonym: "H4K5ac modified histone binding" NARROW []
is_a: GO:0140008 ! H4 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:38:06Z

[Term]
id: GO:0140013
name: meiotic nuclear division
Expand Down Expand Up @@ -450285,6 +450331,30 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
created_by: pg
creation_date: 2017-03-23T14:44:23Z

[Term]
id: GO:0140015
name: H3K14ac histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 acetylated at lysine 14." [PMID:30110338]
synonym: "H3K14ac modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:39:27Z

[Term]
id: GO:0140017
name: H3K18cr histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 crotonylated at lysine 18." [PMID:27105114]
synonym: "H3K18cr modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:41:32Z

[Term]
id: GO:0140018
name: regulation of cytoplasmic translational fidelity
Expand All @@ -450295,6 +450365,18 @@ is_a: GO:1900247 ! regulation of cytoplasmic translational elongation
created_by: pg
creation_date: 2017-04-06T12:27:10Z

[Term]
id: GO:0140019
name: H3K9cr histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 crotonylated at lysine 9." [PMID:27105114]
synonym: "H3K9cr modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:43:48Z

[Term]
id: GO:0140020
name: DNA methyltransferase complex
Expand Down Expand Up @@ -450494,6 +450576,18 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
created_by: pg
creation_date: 2017-05-18T06:29:27Z

[Term]
id: GO:0140038
name: H3K27cr histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 crotonylated at lysine 27." [PMID:27105114]
synonym: "H3K27cr modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:44:30Z

[Term]
id: GO:0140039
name: cell-cell adhesion in response to extracellular stimulus
Expand Down Expand Up @@ -450561,6 +450655,30 @@ intersection_of: has_target_end_location GO:0070056 ! prospore membrane leading
created_by: pg
creation_date: 2017-06-19T09:20:13Z

[Term]
id: GO:0140044
name: H3K18ac histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H3 acetylated at lysine 18." [PMID:30110338]
synonym: "H3K18ac modified histone binding" NARROW []
is_a: GO:0140006 ! H3 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:47:07Z

[Term]
id: GO:0140046
name: H4K16ac histone reader activity
namespace: molecular_function
def: "A histone reader that recognizes a histone H4 acetylated at lysine 16." [PMID:16085498]
synonym: "H4K16ac modified histone binding" NARROW []
is_a: GO:0140008 ! H4 histone reader activity
relationship: has_part GO:0035064 ! methylated histone binding
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29384" xsd:anyURI
created_by: pg
creation_date: 2024-12-06T15:53:35Z

[Term]
id: GO:0140048
name: manganese ion export across plasma membrane
Expand Down Expand Up @@ -455079,7 +455197,7 @@ creation_date: 2020-11-25T16:07:58Z
id: GO:0140566
name: histone reader activity
namespace: molecular_function
def: "A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:32260176, PMID:34726351]
def: "A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]
synonym: "epigenetic reader" BROAD []
synonym: "histone reader" EXACT []
is_a: GO:0140463 ! chromatin-protein adaptor activity
Expand Down

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