After doing :CoverageShow, could you have vim watch whatever .coverage file it loaded results from and immediately notice and reload results if that changes? For example, if you run nosetests --with-coverage outside of vim and that generates new coverage results for the current file, could the plugin immediately discard the stale results and show the fresh ones?
Note we already have #27 to have a manual way to reload coverage, like :CoverageShow!.