MKGCN

MKGCN: a novel method for microbe-drug associations prediction via multiple kernel fusion on graph neural network.

Dataset

1)MDAD: including 2470 clinically or experimentally verified microbe-drug associations, between 1373 drugs and 173 microbes;

2)aBiofilm: including resource of anti-biofilm agents and their potential implications in antibiotic drug resistance;

3)DrugVirust: including the activity and development of related compounds of a variety of human viruses;

Data description

• adj: interaction pairs between microbes and drugs.
• drugs: IDs and names for drugs.
• microbes/viruses: IDs and names for microbes/viruses.
• drugfeatures: pre-processing feature matrix for drugs.
• microbefeatures: pre-processing feature matrix for microbes.
• drugsimilarity: integrated drug similarity matrix.
• microbesimilarity: integrated microbe similarity matrix.

Requirements

• Python 3.7
• Pytorch
• PyTorch Geometric
• numpy
• scipy