purple v3.7

Functional:

• lowered copy number smoothing absolute diff from 2 to 1
• adjust copy number start from diploid region min/max start

Target-regions

• deletion drivers require 3+ depth windows
• TML/B/MSI reworked calculations
• allow partial amps for specific genes: BRAF, EGFR, CTNNB1, CBL, MET, ALK, PDGFRA

Technical:

• provide a dummy zero likelihood for DNDS when a gene isn't present (avoids a crash)

Bugs:

• fixed loading CDKN2A alternative transcript impact VCF tag for somatic and germlime variants