Merge pull request #305 from hlxsites/303-bug-internal-linking-issue

303 Bug internal linking issue for News/Blogs

tools/actions/convert/test/fixtures/blog2-semantic.html

@@ -18,12 +18,12 @@ <h1>9 Essential Products for Streamlining Your mRNA Development and Manufacturin
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- <p>In the realm of life sciences, the tools you employ can significantly influence your work's efficiency and outcomes. For scientists, lab managers, and lab directors involved in mRNA development and manufacturing, having the right instruments at your fingertips can be a game-changer. Here, we spotlight nine indispensable products from <a href="/content/danaher/ls/us/en/about-us/danaher-business-system.html" title="Danaher Business System">Danaher Life Science companies</a> that are revolutionizing this field.</p>
+ <p>In the realm of life sciences, the tools you employ can significantly influence your work's efficiency and outcomes. For scientists, lab managers, and lab directors involved in mRNA development and manufacturing, having the right instruments at your fingertips can be a game-changer. Here, we spotlight nine indispensable products from <a href="/us/en/about-us/danaher-business-system.html" title="Danaher Business System">Danaher Life Science companies</a> that are revolutionizing this field.</p>
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  <h2>1. Biomek i7 Automated Liquid Handlers</h2>
- <p>The <a href="/content/danaher/ls/us/en/products/family/biomek-i7-automated-liquid-handlers.html" title="Biomek i7">Biomek i7 Automated Liquid Handlers</a> are a boon for anyone involved in cell culture, plasmid purification, or analytical assay preparation such as ELISA or NGS. They provide rapid, reliable, and automated liquid handling, freeing scientists to focus on their research rather than time-consuming manual pipetting. Request a quote today to see how the Biomek i7 can enhance your lab's efficiency.</p>
+ <p>The <a href="/us/en/products/family/biomek-i7-automated-liquid-handlers.html" title="Biomek i7">Biomek i7 Automated Liquid Handlers</a> are a boon for anyone involved in cell culture, plasmid purification, or analytical assay preparation such as ELISA or NGS. They provide rapid, reliable, and automated liquid handling, freeing scientists to focus on their research rather than time-consuming manual pipetting. Request a quote today to see how the Biomek i7 can enhance your lab's efficiency.</p>
  <p><a href="/us/en/products/family/biomek-i7-automated-liquid-handlers.html">Learn More</a></p>
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@@ -38,7 +38,7 @@ <h2>1. Biomek i7 Automated Liquid Handlers</h2>
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  <h2>2. Echo 525 Acoustic Liquid Handlers</h2>
- <p>Next up is the <a href="/content/danaher/ls/us/en/products/family/echo-525-acoustic-liquid-handlers.html" title="Echo 525">Echo 525 Acoustic Liquid Handler</a>. This advanced instrument uses sound to precisely transfer liquids without contact, eliminating the risk of cross-contamination and improving the reproducibility of your experiments. Explore the Echo 525 and request a quote to see how it can streamline your lab operations.</p>
+ <p>Next up is the <a href="/us/en/products/family/echo-525-acoustic-liquid-handlers.html" title="Echo 525">Echo 525 Acoustic Liquid Handler</a>. This advanced instrument uses sound to precisely transfer liquids without contact, eliminating the risk of cross-contamination and improving the reproducibility of your experiments. Explore the Echo 525 and request a quote to see how it can streamline your lab operations.</p>
  <p><a href="/us/en/products/family/echo-525-acoustic-liquid-handlers.html">Learn More</a></p>
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@@ -53,7 +53,7 @@ <h2>2. Echo 525 Acoustic Liquid Handlers</h2>
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  <h2>3. Intabio ZT System</h2>
- <p>The <a href="/content/danaher/ls/us/en/products/family/intabio-zt-systems.html" title="Intabio ZT System">Intabio ZT System</a> is a revolutionary tool for the analysis of protein biotherapeutics. It provides rapid, high-resolution analysis of charge variants, enabling you to monitor product quality. Discover how the Intabio ZT System can accelerate your biotherapeutic development and request a quote today.</p>
+ <p>The <a href="/us/en/products/family/intabio-zt-systems.html" title="Intabio ZT System">Intabio ZT System</a> is a revolutionary tool for the analysis of protein biotherapeutics. It provides rapid, high-resolution analysis of charge variants, enabling you to monitor product quality. Discover how the Intabio ZT System can accelerate your biotherapeutic development and request a quote today.</p>
  <p><a href="/us/en/products/family/intabio-zt-systems.html">Learn More</a></p>
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@@ -68,7 +68,7 @@ <h2>3. Intabio ZT System</h2>
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  <h2>4. IDBS Polar</h2>
- <p><a href="/content/danaher/ls/us/en/products/family/polar.html" title="IDBS Polar">IDBS Polar</a> is a cloud-based platform that streamlines the management of your biopharmaceutical data. It integrates seamlessly with your existing systems, providing a single source of truth for your data and enabling real-time collaboration across your organization. Discover how IDBS Polar can revolutionize your data management and request a quote today.</p>
+ <p><a href="/us/en/products/family/polar.html" title="IDBS Polar">IDBS Polar</a> is a cloud-based platform that streamlines the management of your biopharmaceutical data. It integrates seamlessly with your existing systems, providing a single source of truth for your data and enabling real-time collaboration across your organization. Discover how IDBS Polar can revolutionize your data management and request a quote today.</p>
  <p><a href="/us/en/products/family/polar.html">Learn More</a></p>
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@@ -83,7 +83,7 @@ <h2>4. IDBS Polar</h2>
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  <h2>5. Biophase 8800 Capillary Electrophoresis Systems</h2>
- <p>The <a href="/content/danaher/ls/us/en/products/family/biophase-8800-capillary-electrophoresis-systems.html" title="Biophase 8800 Capillary Electrophoresis Systems">Biophase 8800 Capillary Electrophoresis Systems</a> offer high-resolution separation of biomolecules, making them an invaluable tool for protein and nucleic acid analysis. Request a quote to see how the Biophase 8800 can enhance your lab's analytical capabilities.</p>
+ <p>The <a href="/us/en/products/family/biophase-8800-capillary-electrophoresis-systems.html" title="Biophase 8800 Capillary Electrophoresis Systems">Biophase 8800 Capillary Electrophoresis Systems</a> offer high-resolution separation of biomolecules, making them an invaluable tool for protein and nucleic acid analysis. Request a quote to see how the Biophase 8800 can enhance your lab's analytical capabilities.</p>
  <p><a href="/us/en/products/family/biophase-8800-capillary-electrophoresis-systems.html">Learn More</a></p>
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@@ -98,7 +98,7 @@ <h2>5. Biophase 8800 Capillary Electrophoresis Systems</h2>
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  <h2>6. SpectraMax Microplate Readers</h2>
- <p>The <a href="/content/danaher/ls/us/en/products/family/spectramax-id3-id5-series-microplate-readers.html" title="Spectramax iD3/iD5">SpectraMax Microplate Readers</a> provide fast, accurate, and reliable detection of a wide range of assays. With their user-friendly interface and robust data analysis capabilities, they are an essential tool for any lab involved in mRNA development and manufacturing. Explore the SpectraMax series and request a quote to see how they can improve your lab's throughput.</p>
+ <p>The <a href="/us/en/products/family/spectramax-id3-id5-series-microplate-readers.html" title="Spectramax iD3/iD5">SpectraMax Microplate Readers</a> provide fast, accurate, and reliable detection of a wide range of assays. With their user-friendly interface and robust data analysis capabilities, they are an essential tool for any lab involved in mRNA development and manufacturing. Explore the SpectraMax series and request a quote to see how they can improve your lab's throughput.</p>
  <p><a href="/us/en/products/family/spectramax-id3-id5-series-microplate-readers.html">Learn More</a></p>
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@@ -113,7 +113,7 @@ <h2>6. SpectraMax Microplate Readers</h2>
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  <h2>7. ZenoTOF 7600 Mass Spectrometer</h2>
- <p>The <a href="/content/danaher/ls/us/en/products/family/zenotof-7600-systems.html" title="ZenoTOF 7600 Mass Spectrometer">ZenoTOF 7600 Mass Spectrometer</a> provides high-resolution mass spectrometry, allowing you to identify and quantify the molecules in your samples with unparalleled accuracy. Explore the ZenoTOF 7600 and request a quote to see how it can elevate your lab's analytical capabilities.</p>
+ <p>The <a href="/us/en/products/family/zenotof-7600-systems.html" title="ZenoTOF 7600 Mass Spectrometer">ZenoTOF 7600 Mass Spectrometer</a> provides high-resolution mass spectrometry, allowing you to identify and quantify the molecules in your samples with unparalleled accuracy. Explore the ZenoTOF 7600 and request a quote to see how it can elevate your lab's analytical capabilities.</p>
  <p><a href="/us/en/products/family/zenotof-7600-systems.html">Learn More</a></p>
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@@ -128,7 +128,7 @@ <h2>7. ZenoTOF 7600 Mass Spectrometer</h2>
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  <h2>8. BioZen Oligo Analytical HPLC Columns</h2>
- <p>The <a href="/content/danaher/ls/us/en/products/family/biozen-oligo.html" title="Biozen Oligo HPLC Columns">BioZen Oligo Analytical HPLC Columns</a> are designed for the analysis of oligonucleotides, offering excellent resolution and reproducibility. Discover the BioZen Oligo and request a quote to see how it can enhance your lab's analytical capabilities.</p>
+ <p>The <a href="/us/en/products/family/biozen-oligo.html" title="Biozen Oligo HPLC Columns">BioZen Oligo Analytical HPLC Columns</a> are designed for the analysis of oligonucleotides, offering excellent resolution and reproducibility. Discover the BioZen Oligo and request a quote to see how it can enhance your lab's analytical capabilities.</p>
  <p><a href="/us/en/products/family/biozen-oligo.html">Learn More</a></p>
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@@ -143,15 +143,15 @@ <h2>8. BioZen Oligo Analytical HPLC Columns</h2>
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  <h2>9. Skyland PIMS</h2>
- <p>Last but not least, <a href="/content/danaher/ls/us/en/products/family/skyland-pims.html" title="Skyland PIMS">Skyland PIMS</a> is a cloud-based platform that simplifies the management of your process and product data, ensuring compliance with regulatory requirements and facilitating decision-making. Discover how Skyland PIMS can revolutionize your data management and request a quote today.</p>
+ <p>Last but not least, <a href="/us/en/products/family/skyland-pims.html" title="Skyland PIMS">Skyland PIMS</a> is a cloud-based platform that simplifies the management of your process and product data, ensuring compliance with regulatory requirements and facilitating decision-making. Discover how Skyland PIMS can revolutionize your data management and request a quote today.</p>
  <p><a href="/us/en/products/family/skyland-pims.html">Learn More</a></p>
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  <img src="https://s7d9.scene7.com/is/image/danaherstage/card-skyland-pims" alt="">
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- <p>In conclusion, these nine products are revolutionizing <a href="/content/danaher/ls/us/en/solutions/mrna-therapy/mrna-development-manufacturing.html" title="mRNA Development and Manufacturing">mRNA development and manufacturing</a>. By integrating these tools into your workflow, you can accelerate your research, improve your outcomes, and stay at the forefront of life sciences innovation. Explore these products and request a quote today to see how they can transform your lab operations.</p>
+ <p>In conclusion, these nine products are revolutionizing <a href="/us/en/solutions/mrna-therapy/mrna-development-manufacturing.html" title="mRNA Development and Manufacturing">mRNA development and manufacturing</a>. By integrating these tools into your workflow, you can accelerate your research, improve your outcomes, and stay at the forefront of life sciences innovation. Explore these products and request a quote today to see how they can transform your lab operations.</p>
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@@ -19,10 +19,10 @@ <h1>Gene Editing in Organoids: Accounting for Complexity in Drug Discovery</h1>
  <img src="https://s7d9.scene7.com/is/image/danaherstage/gene-editing-in-organoids" alt="Gene Editing in Organoids">
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  <p>The genome is the blueprint for life, consisting of genes made up of thousands of pairs of DNA bases. Altering one base pair can drastically change how the gene’s protein product functions, while mutations can lead to the development of a range of genetic disorders.</p>
- <p><strong><a href="/content/danaher/ls/us/en/library/crispr-cas9.html">CRISPR</a></strong> allows researchers to target and edit specific genes in order to better understand the genome, human diseases and the effects of specific mutations. The development of CRISPR has opened the door to ending diseases by fixing mutations and developing therapies through the process of modeling mutations. Scientists use complex gene editing and disease modeling systems to gain insights on the potential of CRISPR.</p>
+ <p><strong><a href="/us/en/library/crispr-cas9.html">CRISPR</a></strong> allows researchers to target and edit specific genes in order to better understand the genome, human diseases and the effects of specific mutations. The development of CRISPR has opened the door to ending diseases by fixing mutations and developing therapies through the process of modeling mutations. Scientists use complex gene editing and disease modeling systems to gain insights on the potential of CRISPR.</p>
  <p>Most gene editing studies are performed in traditional 2D culture systems that model a simplified version of the tissue and biology in question. These 2D culture systems typically consist of one cell type that forms into a single layer of cells. While these studies demonstrate how one cell type behaves when a gene’s sequence is altered, their simplified nature makes it difficult to know how that cell, or the entire tissue, would respond within the body when that same sequence is altered. The need for greater complexity of cell-based systems has led to the development of organoids.</p>
  <h3>What are organoids?</h3>
- <p>Organoids are 3D tissue models consisting of multiple cell types that could bridge the gap between traditional 2Din vitrocultures and the actualin vivotissue of the body. <a href="/content/danaher/ls/us/en/library/organoids.html">Organoids</a> are developed using primary tissues or induced pluripotent <a href="/content/danaher/ls/us/en/library/stem-cells.html">stem cells</a> (iPSCs) derived from standard iPSC cell lines or from cells of patients that carry particular diseases. Typically, iPSCs are developed from blood or skin cell samples, and then differentiated into organoids representing various tissues from the liver, intestine, heart, brain, and other organs. Organoids can also be grown from adult tissues that originate in the intestine or liver, for example, and represent normal or malignant tissues. Developing organoids from human cell sources offers distinct advantages over other commonly used systems like animal models. While animal models are useful for modelingin vivoresponses, the physiological differences between animals and humans make disease modeling and drug efficacy studies less relevant and less predictive. They also present ethical, monetary, and time-related challenges.</p>
+ <p>Organoids are 3D tissue models consisting of multiple cell types that could bridge the gap between traditional 2Din vitrocultures and the actualin vivotissue of the body. <a href="/us/en/library/organoids.html">Organoids</a> are developed using primary tissues or induced pluripotent <a href="/us/en/library/stem-cells.html">stem cells</a> (iPSCs) derived from standard iPSC cell lines or from cells of patients that carry particular diseases. Typically, iPSCs are developed from blood or skin cell samples, and then differentiated into organoids representing various tissues from the liver, intestine, heart, brain, and other organs. Organoids can also be grown from adult tissues that originate in the intestine or liver, for example, and represent normal or malignant tissues. Developing organoids from human cell sources offers distinct advantages over other commonly used systems like animal models. While animal models are useful for modelingin vivoresponses, the physiological differences between animals and humans make disease modeling and drug efficacy studies less relevant and less predictive. They also present ethical, monetary, and time-related challenges.</p>
  <p>Organoids avoid these challenges by modeling human tissue using human cells. They also capture the tissue environment more closely than 2D cultures by growing 3D cell structures that mimic the organs they are modeling. One of the ways that organoids capture the tissue micro-environment is by featuring more than one cell type. For example, cardiac organoids include cardiac cells, vascular cells and fibroblasts. This is important for observing how cells interact during tissue-level events like inflammation, which contributes to complex conditions like myocardial infarction and stroke. Modeling not only how cardiac cells, but also immune and vascular cells respond to inflammation will provide a more complete picture, especially valuable in the drug development process.</p>
  <p>Organoids capture the complexity of real tissue not only by including multiple cell types, but also by displaying a morphological structure that closely mimics the real tissue organisation. For instance, intestinal organoids mimic the crypts that line the intestine, while brain organoids mimic the different neural layers of the brain.</p>
  <p>The structures of organoids also make them useful for studying drug penetration, which is important for predicting drug efficiency. Small molecule drugs or biologics need to be delivered via blood vessels and penetrate tissue to get into cells. In 2D cultures, drugs are entered directly into cells, giving no indication of how the drug will penetrate live tissue. Organoids are more suitable for demonstrating how a drug will behave within a live organ.</p>