FY22 Work

Release v1.1 of current browser

• release of a script- and container-based command line tool that
  • operates on locally (both input and output)
  • takes as input hiC and genome data
  • runs MD simulation to produce a structure file
  • creates ‘project’ needed to run the current 4DGB

Update core 4DGB technologies to handle human genome-sized datasets

• Application framework moved to Dash
  • Redesign of structure viewer to be Dash component
  • Redesign of hi-C viewer to be Dash component
• Design of new genome viewer-based interactions
  • Views entire genome in a more abstract way
  • Connected to one or more structure viewers
• Database redesign for larger data
• Redesign of server API to more SQL-based approach (?)

Deliverables by the end of FY22

• 4D Genome Browser command line tool supporting end-to-end workflow (hiC to viewer) on local files
  • [July 15] Paper on 4D Genome Browser command line tool
• Core technologies updated for human genome-sized dataset handling
  • Redesign of underlying database, server API
  • New 'Genome viewer' component to show high level, abstract view of the entire genome
  • 'Structure view' and 'contact map view' refactoring to Dash framework