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Add MAXO Annotation ingest #798

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3 of 6 tasks
Tracked by #714
kevinschaper opened this issue Sep 3, 2024 · 3 comments
Open
3 of 6 tasks
Tracked by #714

Add MAXO Annotation ingest #798

kevinschaper opened this issue Sep 3, 2024 · 3 comments
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@kevinschaper
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kevinschaper commented Sep 3, 2024

Create an initial MAXO annotation ingest.

Process is started here: https://github.com/monarch-initiative/maxo-annotation-ingest

This one felt natural to start with doc, then move into tests, then implementation

A draft PR for adding medical action entity & association classes to the biolink model biolink/biolink-model#1523

This may go into the September release using high level classes like Association and NamedThing

  • download yaml
  • transform python
  • transform yaml
  • tests
  • documentation
  • import into monarch-ingest
@kevinschaper
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kevinschaper commented Nov 2, 2024

@sierra-moxon I'm getting stuck on how to capture a CHEBI extension id of a MAXO term.

If the MAXO term is calcium channel blocking agent therapy (MAXO:0000434) and the CHEBI term is 2,4-diaminopyridine (CHEBI:51599), I'm guessing that's saying that this particular chemical is used for the therapy? So then, this is a qualifier that is making the subject more specific?

maybe subject_derivative_qualifier, because this is a post-composition that means calcium channel blocking agent therapy with 2,4-diaminopyridine?

@iimpulse does that meaning sound right from your end?

@iimpulse
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iimpulse commented Nov 5, 2024

Yeah sounds right. Sometimes it can be less specific though. Drug Therapy and then some specific drug. But I dont think that changes anything here. Just something to think about

@sierra-moxon
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new release of biolink out with specialization_qualifiers to hold MAXO terms.

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