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Phlya authored Mar 22, 2019
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## Installation
All requirements apart from `cooltools` are available from PyPI or conda. For `cooltools`, do

```
`
pip install https://github.com/mirnylab/cooltools/archive/master.zip
```
`

For coolpuppy (and other dependencies) simply do:

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Currently, `coolpup.py` doesn't support inter-chromosomal pileups, but this is an addition that is planned for the future.

## Citing coolpup.py

Until it has been published in a peer-reviewed journal, please cite our preprint

**Coolpup.py - a versatile tool to perform pile-up analysis of Hi-C data**

Ilya M. Flyamer, Robert S. Illingworth, Wendy A. Bickmore

https://www.biorxiv.org/content/10.1101/586537v1

## This tool has been used in the following publications

**DNA methylation directs polycomb-dependent 3D genome re- organisation in naive pluripotency**

Katy A McLaughlin, Ilya M Flyamer, John P Thomson, Heidi K Mjoseng, Ruchi Shukla, Iain Williamson, Graeme R Grimes, Robert S Illingworth, Ian R Adams, Sari Pennings, Richard R Meehan, Wendy A Bickmore

https://www.biorxiv.org/content/early/2019/01/22/527309
https://www.biorxiv.org/content/10.1101/527309v1

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