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BUG update genewise dispersions and fitted dispersions of refitted genes #274

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merged 1 commit into from
Apr 25, 2024

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BorisMuzellec
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@BorisMuzellec BorisMuzellec commented Apr 23, 2024

What does your PR implement? Be specific.

Currently, when outlier genes are refitted, only "_normed_means", "LFC" and "dispersions" are updated in the fields of the DeseqDataSet, but not "genewise_dispersions" and "fitted_dispersions".

This has limited or no impact on the remainder of the code, but interferes with visualisation (e.g. with plot_dispersions().

This PR fixes this by also updating "genewise_dispersions" and "fitted_dispersions".

Example

Before:

Capture d’écran 2024-04-24 à 10 20 25

After:

Capture d’écran 2024-04-24 à 10 42 06

@BorisMuzellec BorisMuzellec marked this pull request as ready for review April 24, 2024 08:49
@BorisMuzellec BorisMuzellec requested review from a user and umarteauowkin April 24, 2024 08:49
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LGTM, thanks @BorisMuzellec

@BorisMuzellec BorisMuzellec merged commit 44fa959 into main Apr 25, 2024
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@BorisMuzellec BorisMuzellec deleted the fix/refitted_trend_curve_dispersions branch April 25, 2024 08:24
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2 participants