Slides for talk on scientific irreproducibility

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Thesis:

Flexible research designs + Low statistical power = poor reliability in biomedical resaerch.

Outline

• Null hypothesis significance testing
  • Pitfall 1: Misuse of p-values
  • Pitfall 2: Researcher degrees of freedom
• Positive predictive value of research findings
• Poor Replication Rates
• Modernizing academic data science
• Discussion