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Gnom AD v3.1 and v4.0 VCF converter #58

Merged
merged 4 commits into from
Apr 15, 2024
Merged

Gnom AD v3.1 and v4.0 VCF converter #58

merged 4 commits into from
Apr 15, 2024

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ManuelTgn
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Enhancements

  • Improved compatibility with gnomAD v4.0 VCFs.
  • Decreased conversion running time through optimization of VCF read/write operations.
  • Employ TBI indexes for efficient VCF parsing and queries.
  • Employ pysam library for enhanced VCF parsing and efficient VCF data management.

Caveats

  • Add pysam 0.22.0 to the list of dependencies required to build CRISPRme in the bioconda recipe.

@ManuelTgn ManuelTgn added the enhancement New feature or request label Apr 15, 2024
@ManuelTgn ManuelTgn self-assigned this Apr 15, 2024
@samuelecancellieri samuelecancellieri merged commit 5b4a86f into main Apr 15, 2024
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@ManuelTgn ManuelTgn deleted the gnomAD-v4-converter branch August 21, 2024 08:23
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@samuelecancellieri samuelecancellieri Awaiting requested review from samuelecancellieri

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@ManuelTgn ManuelTgn

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@ManuelTgn @samuelecancellieri