Skip to content
@pirl-unc

Personalized Immunotherapy Research Lab @ UNC

Collective of researchers at UNC-CH who combine experimental and computational approaches to develop new immunotherapies and bring them into the clinic.
README.md

PIRL

The Personalilized Immunotherapy Research Lab (PIRL) is a multi-PI research group at the University of North Carolina - Chapel Hill. We work on identifying the determinants immune-mediated tumor clearance in a way that's fully personalized to each individual and their cancer. That high degree of personalization is manifested in algorithms for antigen identification across the spheres of genomics, proteomics, and machine learning for immunology.

Pinned Loading

  1. mhcgnomes mhcgnomes Public

    Parsing MHC nomenclature in the wild

    Python 16 3

  2. ace ace Public

    Jupyter Notebook 2 1

  3. defense-against-the-dark-arts defense-against-the-dark-arts Public

    Course website and resources for BCB 731

    HTML

  4. golfy golfy Public

    Heuristic solver for pooled peptide experiment design

    Jupyter Notebook 1

  5. lens lens Public

    Landscape of Effective Neoantigens Software

  6. are-we-good are-we-good Public

    CI status of every project we develop and/or help maintain

Repositories

Showing 10 of 74 repositories
  • pirlygenes Public

    Gene sets used for cancer immunotherapy expression analysis

    pirl-unc/pirlygenes’s past year of commit activity
    Jupyter Notebook 0 Apache-2.0 0 0 0 Updated Nov 26, 2024
  • nexus Public
    pirl-unc/nexus’s past year of commit activity
    Nextflow 1 0 0 0 Updated Nov 26, 2024
  • longread-fusion-transcript-pipeline Public
    pirl-unc/longread-fusion-transcript-pipeline’s past year of commit activity
    Shell 0 0 0 0 Updated Nov 15, 2024
  • tcr_translate Public Forked from dhuvik/tcr_translate

    Accompanying Repository to TCR-TRANSLATE paper.

    pirl-unc/tcr_translate’s past year of commit activity
    Python 1 1 0 0 Updated Nov 13, 2024
  • lens Public

    Landscape of Effective Neoantigens Software

    pirl-unc/lens’s past year of commit activity
    0 0 0 0 Updated Nov 12, 2024
  • TCRpMHCdataset Public

    Python Class for Handling Many-to-Many Nature of TCR::pMHC Data

    pirl-unc/TCRpMHCdataset’s past year of commit activity
    Python 1 Apache-2.0 1 0 0 Updated Nov 10, 2024
  • pdf-reports Public

    Helping code for compiling plots and other outputs into presentation pdfs.

    pirl-unc/pdf-reports’s past year of commit activity
    R 0 GPL-3.0 0 0 0 Updated Nov 4, 2024
  • vstol Public
    pirl-unc/vstol’s past year of commit activity
    Python 0 0 1 0 Updated Oct 15, 2024
  • nutm1-fusions Public

    Hunting for T-cell epitopes in recurrent NUTM1 somatic fusions

    pirl-unc/nutm1-fusions’s past year of commit activity
    Jupyter Notebook 0 Apache-2.0 0 0 0 Updated Oct 7, 2024
  • mhcgnomes Public

    Parsing MHC nomenclature in the wild

    pirl-unc/mhcgnomes’s past year of commit activity
    Python 16 Apache-2.0 3 8 1 Updated Oct 7, 2024
View all repositories

Top languages

Loading…

Most used topics

Loading…