I'm curious what you think of the issue I raised on asyncssh project
ronf/asyncssh#760
In short; hosts built with oracle linux 8 use OpenSSL 1.1.1k, and these have had a 5x fold or more increase in establishing a connection for all versions of cryptography above v41 (i.e v42 - v45). So pip installing v41 clears the issue and pip installing v45 reveals the issue in the tests (details in the asyncssh ticket).
oracle linux 9 however, uses OpenSSL 3.0.7, and we don't see this issue across any version of cryptography.
Many thanks