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MMseqs2 Release 3-be8f6

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@martin-steinegger martin-steinegger released this 28 May 08:11
· 2471 commits to master since this release

Changes since 2-23394 Release

New Features

  • Create simple workflows fasta/fastq in flat file out for clustering easy-cluster and searching easy-search
  • Add a new clustering greedy incremental clustering algorithm to the clust module which needs less memory
  • Make the new low memory clustering algorithm default if --cov-mode 1 is used in linclust and cluster
  • Add alignall module for all-against-all alignments of e.g. clusters
  • Improved Windows support
  • filterdb learned new modes

Bug fixes

  • Fix wrong merging code in linclust
  • Fix e-value issues in target-split case
  • Fix seg. fault in rescore diagonal if 'z' is used
  • Fix seg. fault when using masking in kmermatcher
  • Fix wrong filterdb default mode
  • prefilter overestimated the required amount of memory and refused to run
  • prefilter scores would saturate to early, now they have the full 2^16 range

Others

  • Profile searches do create less high scoring false positive through better compositional bias correction and masking of low complexity regions of profiles
  • Clustering supports now the whole 2^32 range instead the previously 2^31
  • Speed up clustering when using --cov-mode 1
  • Rework symlinks to the header databaes
  • Support profiles on query and target side in result2profile