Merge pull request #88 from steno-aarhus/new-proposal-bhi

Project proposal: bhi

data-raw/projects/proposals/bhi.yaml

@@ -0,0 +1,23 @@
+submitted_on: '2024-08-29'
+full_name: Nuno Nogueira
+github_username: nunonog
+job_position: Postdoc researcher
+phd_supervisor: ''
+affiliation: Aarhus University
+project_title: 'Investigating the Impact of Family-Based BMI Divergence on Premature
+  Mortality: Development and Application of a Pedigree-Based Homeostatic Index'
+project_description: The proposed project seeks to explore how deviations from an
+  individual’s genetically-determined BMI, as calculated through familial relationships,
+  influence the risk of premature mortality. By constructing a family-based BMI Homeostatic
+  Index (BHI), we aim to capture the genetically-determined BMI for each individual
+  using data from multiple generations within families. This index will serve as a
+  measure of how much an individual’s BMI deviates from what would be expected based
+  on their genetic background.The project involves calculating the BHI by analyzing
+  BMI data across family members, taking into account the degree of relatedness between
+  individuals. By using a pedigree-based approach, the BHI will quantify the divergence
+  of an individual's BMI from their family's average, adjusted for factors such as
+  age and sex. This approach allows us to assess whether these deviations are associated
+  with increased mortality risk, offering insights into the genetic basis of obesity
+  and its health consequences.
+agree_to_conditions: 'Yes'
+