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fix: typos
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sgibb committed Dec 17, 2023
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2 changes: 1 addition & 1 deletion sections/03-methods.Rmd
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## Study design and population

In this prospective observational single-center study, we evaluated the occurrence of CRT in critically ill pateints with CVCs treated in our surgical intensive care unit (ICU)
In this prospective observational single-center study, we evaluated the occurrence of CRT in critically ill patients with CVCs treated in our surgical intensive care unit (ICU)
at a university hospital during a six-month period from March 2022 to August 2022.

We enrolled all adult patients (≥ 18 years) who required a CVC for at least 48 hours.
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2 changes: 1 addition & 1 deletion sections/04-results.Rmd
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Expand Up @@ -62,7 +62,7 @@ In addition to the univariate analyses we applied multiple regression analyses t
All variables with missing values were omitted to maintain the sample size.
However, the results don't vary much even when all variables are included (see Supplement for a regression with half the number of samples but all the variables).

As shown in the forest plot (see Figure \ref(fig:forestplot)), the Arrow4 and Vygon5 CVC types were significantly associated with higher rates of CRT.
As shown in the forest plot (see Figure \@ref(fig:forestplot)), the Arrow4 and Vygon5 CVC types were significantly associated with higher rates of CRT.
Their hazard ratios were `r format(exp(rgcx$coefficients["ManLuArrow4"]), digits = 2)` and `r format(exp(rgcx$coefficients["ManLuVygon5"]), digits = 2)`, respectively.
In addition to CVC type, no prophylactic anticoagulation prior to CVC placement was another significant risk factor for CRT, with a hazard ratio of `r format(exp(rgcx$coefficients["AnticoagulationGroupNone"]), digits = 2)`.
Cancer was also significantly associated with CRT (hazard ratio `r format(exp(rgcx$coefficients["AnticoagulationGroupNone"]), digits = 2)`), but is an inhomogeneous disease category.
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