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Lower default min candidate size to 8
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ctsa committed Apr 4, 2014
1 parent f03fa00 commit eaed4d7
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2 changes: 2 additions & 0 deletions ChangeLog.txt
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v0.20.1
- Lower default min candidate size to 8
v0.20.0
- MANTA-136 turn on conservative large insertion calling
- MANTA-126 multi-junction SV scoring
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4 changes: 2 additions & 2 deletions src/markdown/mantaUserGuide.md
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Expand Up @@ -72,7 +72,7 @@ levels and take other RNA-specific filtration and intron handling steps.

Manta is able to detect all variation classes which can be explained as
novel DNA adjacencies in the genome. Simple insertion/deletion events can be
detected down to a configurable minimum size cutoff (defaulting to 10). All DNA
detected down to a configurable minimum size cutoff (defaulting to 8). All DNA
adjacencies are classified into the following categories based on the breakend
pattern:

Expand Down Expand Up @@ -157,7 +157,7 @@ is provided. These files are:
evidence is required for a SV to be entered as a candidate. An SV or indel
must be a candidate to be considered for scoring, therefore an SV cannot
appear in the other VCF outputs if it is not present in this file. Note that
by default this file includes indels down to a very small size (>= 10 bases).
by default this file includes indels down to a very small size (>= 8 bases).
These are intended to be passed on to a small variant caller without scoring
by manta itself (by default manta scoring starts at size 51).
* __diploidSV.vcf.gz__
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2 changes: 1 addition & 1 deletion src/python/bin/configManta.py.ini
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referenceFasta = /illumina/development/Isis/Genomes/Homo_sapiens/UCSC/hg19/Sequence/WholeGenomeFasta/genome.fa

# Run discovery and candidate reporting for all SVs/indels at or above this size:
minCandidateVariantSize = 7
minCandidateVariantSize = 8

# After candidate identification, only score and report SVs/indels at or above this size:
minScoredVariantSize = 51
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