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Substantial updates to the splatPop simulation (from @azodichr)
Added ability to simulate data with complex multiplexed sequencing designs
Added simulation of “conditional” effects, where a subset of DE and eQTL effects are applied to only a subset of individuals (e.g. disease vs. healthy samples)
Added the ability to simulate different numbers of cells for each sample, sampled from a gamma distribution.
Updates to the splatPop vignette describing these changes
Logical matrices should now be handled correctly when minimising output SingleCellExperiment objects