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I had some problems with partitioning in GATK which boiled down to the ordering of the reference sequence dictionary. I think a fasta dict file has an order, so it would be good to be consistent with that if possible.
fnothaft
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Apr 29, 2017
The order of the contigs in a dictionary produced from TwoBitFile is not the same as the order they are stored in in the .2bit file.
I think the problem is the records are being stored in a standard map, rather than one that preserves insertion order (like ListMap).
See https://github.com/bigdatagenomics/adam/blob/master/adam-core/src/main/scala/org/bdgenomics/adam/util/TwoBitFile.scala#L70
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