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Change names of monomers #5323

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57 tasks done
ljubica-milovic opened this issue Aug 20, 2024 · 1 comment · Fixed by #5619
Closed
57 tasks done

Change names of monomers #5323

ljubica-milovic opened this issue Aug 20, 2024 · 1 comment · Fixed by #5619

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@ljubica-milovic
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ljubica-milovic commented Aug 20, 2024

Peptides

  • 3-(3-pyridyl)-alanine
  • D-3-(2-naphthyl)-alanine
  • N-methyl-beta-alanine
  • (2S)-6-amino-2-hydroxyhexanoic acid
  • alpha-methyl-tyrosine
  • D-Lactic acid #5195
Symbol Old name New name
3Pal 3-(2-pyridyl)-alanine 3-(3-pyridyl)-alanine
D-2Nal D-3-(2-naphtyl)-alanine D-3-(2-naphthyl)-alanine
NMebAl 3-(methylamino)propanoic acid N-methyl-beta-alanine
DALys 6-amino-2-hydroxyhexanoic acid (2S)-6-amino-2-hydroxyhexanoic acid
aMeTyr L-metyrosine alpha-methyl-tyrosine
D-OAla D-lactic acid D-Lactic acid

Phosphates

  • N1,N1-dimethylethane-1,2-diamine
  • Hydroxymethylphosphonic acid
  • Methylphosphonothioic acid
  • Dihydrogen phosphate
  • Dihydrogen phosphorothioate
  • Ethylenediamine
  • Oxy
Symbol Old name New name
m2nen (Dimethylaminoethyl)amino N1,N1-dimethylethane-1,2-diamine
mepo2 Methylenephosphonate Hydroxymethylphosphonic acid
msp Methylthiophosphonate Methylphosphonothioic acid
P- (old symbol: naP) Sodium Phospate Dihydrogen phosphate
sP- (old symbol: nasP) Sodium Phosphothiotate Dihydrogen phosphorothioate
nen (Aminoethyl)amino Ethylenediamine
oxy Oxy (ether) Oxy

Bases

  • 6-Mercaptopurine
  • (E)-5-(2-bromovinyl)uracil
  • 2-hydroxypyrimidine
  • 5-DBCO-U
  • 5-[(methylamino)methyl]uracil
  • 5-Thiazoleuracil
  • 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione
  • tetrahydro-4-hydroxy-1H-pyrimidin-2-one
  • (4R)-tetrahydro-4-hydroxy-1H-pyrimidin-2-one
  • N1-methyl-pseudouracil
  • 4-Cyanoethylthiothymine
  • N9-allyl-8-oxoguanine
  • N1-methylguanine
  • N2,N2-dimethylguanine
  • N2-methylguanine
  • 6-O-methylguanine
  • N7-methylguanine
  • N7-methyl-8-dihydroguanine
  • 5-methylcytosine
  • N4-acetylcytosine
  • G-clamp
  • guanidino-G-clamp
  • 4N-Hydroxycytosine
  • 8-azidoadenine
  • N6-benzyladenine
  • N6-cyclopropylmethyladenine
  • N6-cyclohexyladenine
  • N6-cyclopentyladenine
  • N6,N6-dimethyladenine
  • 2-amino-6-etoxypurine
  • N6-ethyladenine
  • 2-(1-(3-aminopropyl)imidazole)adenine
  • N1-methyladenine
  • N3-(dimethylamino)propylaminoadenine
  • N6-methyladenine
Symbol Old name New name
s6puri 6-Thiopurine 6-Mercaptopurine
brviny 5-(2-Bromovinyl)uracil (E)-5-(2-bromovinyl)uracil
d4U 4-Deoxouracil 2-hydroxypyrimidine
DBCOnC 5-DBCO-U (ethylene carbamoyl hexylamino linker) 5-DBCO-U
mnm5U 5-[(Methylamino)methyl]uridine 5-[(methylamino)methyl]uracil
thiz5U 5-Thiazoleuridine 5-Thiazoleuracil
pr56U 5,6-Propylene uracil 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione
h456U 4,5,6-trihydrouracil tetrahydro-4-hydroxy-1H-pyrimidin-2-one
h456UR (R)-4,5,6-trihydrouracil (4R)-tetrahydro-4-hydroxy-1H-pyrimidin-2-one
m1Yra 1-Methyl-pseudouracil N1-methyl-pseudouracil
cnes4T 4-Cyanoethylthiothymidine 4-Cyanoethylthiothymine
allyl9 9-Allylguanine N9-allyl-8-oxoguanine
m1G 1-Methylguanine N1-methylguanine
m22G 2,2-Dimethylguanine N2,N2-dimethylguanine
m2G 2-Methylguanine N2-methylguanine
m6G 6-Methylguanine 6-O-methylguanine
m7G 7-Methylguanine N7-methylguanine
m7h8G 7-Methyl 8-dihydroguanine N7-methyl-8-dihydroguanine
5meC 5-methyl-cytidine 5-methylcytosine
ac4C 4-Acetylcytosine N4-acetylcytosine
gclamp G-clamp (9-(aminoetoxy)phenoxazine) G-clamp
ggclam G-clamp (9-(guanylethoxy)phonoxazine guanidino-G-clamp
oh4C 4-N-Hydroxycytosine 4N-Hydroxycytosine
az8A Azidoadenine 8-azidoadenine
baA N-benzyl-adenine N6-benzyladenine
cmpA N-cyclopropylmethyl-adenine N6-cyclopropylmethyladenine
cyh6A 6-Cyclohexyladenine N6-cyclohexyladenine
cyp6A 6-Cyclopentyladenine N6-cyclopentyladenine
daA N,N-dimethyl-Adenine N6,N6-dimethyladenine
e6A 6-Ethyladenine 2-amino-6-etoxypurine
eaA N-ethyl-adenine N6-ethyladenine
imprn2 N-(Aminopropyl)imidazoleadenine 2-(1-(3-aminopropyl)imidazole)adenine
m1A 1-Methyladenine N1-methyladenine
m2nprn 3-(Dimethylamino)propylaminoadenine N3-(dimethylamino)propylaminoadenine
meA N-Methyl-Adenine N6-methyladenine

Sugars

  • 1',2'-dideoxyribose
  • Ribose (2,5 connectivity)
  • 6-FAM (3' end)
  • Thiol Modifier 6 S-S (3' end)
  • 2-(methylamino)acetamidate (5' end)
  • 6-FAM (5' end)
  • N-acetyl-2-deoxyazaribose
  • 2-ethyl-2-deoxyribose
  • Ara-FHNA
Symbol Old name New name
12ddR 1',2'-Di-Deoxy-Ribose 1',2'-dideoxyribose
25R 2,5-Ribose Ribose (2,5 connectivity)
3FAM 3-FAM 6-FAM (3' end)
3SS6 3'-Thiol-Modifier 6 S-S from Glen Research Thiol Modifier 6 S-S (3' end)
5cGT 2-(methylamino)acetamidate (GeneTools 5'-cap for PMO) 2-(methylamino)acetamidate (5' end)
5FAM 5'-6FAM (6-carboxyflurescein) 6-FAM (5' end)
acn4d 4-Acetylamino-2-deoxyribose N-acetyl-2-deoxyazaribose
Ae2d 2-alpha-C-ethyl-2-deoxyribose 2-ethyl-2-deoxyribose
afhna 3-ara FHNA Ara-FHNA
@ljubica-milovic ljubica-milovic self-assigned this Aug 20, 2024
rrodionov91 added a commit that referenced this issue Oct 1, 2024
#5324 - Change symbols of monomers

#5323 - Change names of monomers

#5195 - Some content problems in monomer library

#5111 - Change structure of monomers
@rrodionov91 rrodionov91 linked a pull request Oct 1, 2024 that will close this issue
9 tasks
rrodionov91 added a commit that referenced this issue Oct 3, 2024
#5325 - Change natural analogue of monomers
#5324 - Change symbols of monomers
#5323 - Change names of monomers
#5195 - Some content problems in monomer library
#5111 - Change structure of monomers

---------

Co-authored-by: Alexey Girin <agirin@mail.ru>
@AlexeyGirin
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Verified.

Versions

  • Ketcher Version 2.26.0-rc.1 Build at 2024-10-04; 18:45:04
  • Indigo Toolkit Version 1.25.0-rc.1.0-g704673fcb-wasm32-wasm-clang-19.0.0
  • Chrome Version 129.0.6668.90 (Official Build) (64-bit)
  • Win10

Guch1g0v pushed a commit that referenced this issue Oct 17, 2024
#5325 - Change natural analogue of monomers
#5324 - Change symbols of monomers
#5323 - Change names of monomers
#5195 - Some content problems in monomer library
#5111 - Change structure of monomers

---------

Co-authored-by: Alexey Girin <agirin@mail.ru>
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