32: Sample data: SEEG recording during music listening
Music is a potent means in shaping our emotion, perception, and cognition. We attempt to elucidate the neural substrates of music perception by high spatiotemporal recording of neuron populations using stereo-electroencephalography (SEEG), an invasive procedure to delineate epileptic onset zones in medically refractory patients. Here are representative recordings from a few patients and the presented musical pieces. These data can disclose how brain activity is orchestrated with the acoustic inputs.
All patients and participants joined this study with written informed consents after the approval of the Institute Review Board of Taipei Veteran General Hospital. Auditory stimulus including three songs (Song 1: “Doraemon” theme song, Song 2: “Brahms Piano Concerto No. 1”, and Song 3: “Lost stars” from Adam Levine). Each participant listened to each song twice in a randomized order.
The acoustic stimuli are here:
| Doraemon theme | Brahams Piano Concerto No. 1 | Lost stars |
|---|
Electrophysiological responses were measured from six epilepsy patients by stereotactic electroencephalography (sEEG). All patients had an electrode (Ad-Tech Medical Instrument, Oak Creek, WI, USA) with up to eight contacts (5 mm separation) at the temporal lobe. Pre-surgery and post-surgery structural MRI’s were obtained from patients to identify electrode and contacts locations. The same three songs were presented to each patient, who listened to each song twice in a randomized order.
MRI data were acquired on a 3T MRI systems (Skyra, Siemens) with a 32-channel whole-head coil array. Structural images were acquired with MPRAGE in a 1-mm isotropic resolution before and after electrode implantation.
| Patient | SEEG data (Matlab) | Electrode locations (Matlab) | Pre-implantation MRI (FreeSurfer) | Post-implantation MRI (FreeSurfer) |
|---|---|---|---|---|
| s025 | SEEG data | Electrode locations | Pre-implantation MRI | Post-implantation MRI |
| s031 | SEEG data | Electrode locations | Pre-implantation MRI | Post-implantation MRI |
| s035 | SEEG data | Electrode locations | Pre-implantation MRI | Post-implantation MRI |
The SEEG data consists of variable erf_all, which includes the SEEG measurements in six measurements (three songs; two repetition). For example, the field trig_str "D1" indicates the measurements for Doraemon theme for the first listening. There are "D" (Doraemon theme), "B" (Brahams piano concerto), and "L" (Lost stars) with either "1" (first listening) or "2" (second listening) post-fix. The erf field is a 2D matrix (n_channel x n_time points) storing the SEEG data. Electrode and contact names are stored in name field. A time vector for the SEEG measurement is stored in the timeVec field.
The electrode locations are stored in the electrode variable. For each electrode, there are name, spacing, n_contact, and coord fields for each electrode for its name, spacing between contacts (in mm), the number of contacts on the electrode, and coordinates, respectively. The coordinates are in FreeSurfer surface coordinates for each patient. See this page for coordinate transformation. To render eletrode contacts on the pre-implantation FreeSurfer MRI model, please consult this script, which shows the patient s035 brain surface with electrodes. Electrodes and view navigation can be enabled by click e and g keys over the brain visualization window, respectively.
