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@daviesrob daviesrob released this 21 Feb 14:31
· 305 commits to develop since this release
1.17
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Download the source code here: htslib-1.17.tar.bz2.(The "Source code" downloads are generated by GitHub and are incomplete as they are missing some generated files.)

  • A new API for iterating through a BAM record's aux field. (PR #1354, addresses #1319. Thanks to John Marshall)

  • Text mode for bgzip. Allows bgzip to compress lines of text with block breaks at newlines. (PR #1493, thanks to Mike Lin for the initial version PR #1369)

  • Make tabix support CSI indices with large positions. Unlike SAM and VCF files, BED files do not set a maximum reference length which hindered CSI support. This change sets an arbitrary large size of 100G to enable it to work. (PR #1506)

  • Add a fai_line_length function. Exposes the internal line-wrap length. (PR #1516)

  • Check for invalid barcode tags in fastq output. (PR #1518, fixes samtools/samtools#1728. Reported by Poshi)

  • Warn if reference found in a CRAM file is not contained in the specified reference file. (PR #1517 and PR #1521, adds diagnostics for #1515. Reported by Wei WeiDeng)

  • Add a faidx_seq_len64 function that can return sequence lengths longer than INT_MAX. At the same time limit faidx_seq_len to INT_MAX output. Also add a fai_adjust_region to ensure given ranges do not go beyond the end of the requested sequence. (PR #1519)

  • Add a bcf_strerror function to give text descriptions of BCF errors. (PR #1510)

  • Add CRAM SQ/M5 header checking when specifying a fasta file. This is to prevent creating a CRAM that cannot be decoded again. (PR #1522. In response to samtools/samtools#1748 though not a direct fix)

  • Improve support for very long input lines (> 2Gbyte). This is mostly useful for tabix which does not do much interpretation of its input. (PR #1542, a partial fix for #1539)

  • Speed up load_ref_portion. This function has been sped up by about 7x, which speeds up low-depth CRAM decoding by about 10%. (PR #1551)

  • Expand CRAM API to cope with new samtools cram_size command. (PR #1546)

  • Merges neighbouring I and D ops into one op within pileup. This means 4M1D1D1D3M is reported as 4M3D3M. Fixing this in sam.c means not only is samtools mpileup now looking better, but any tool using the mpileup API will be getting consistent results. (PR #1552, fixes the last remaining part of samtools/samtools#139)

  • Update the API documentation for bgzf_mt as it refered to a previous iteration. (PR #1556, fixes #1553. Reported by Raghavendra Padmanabhan)

Build changes

  • Use POSIX grep in testing as egrep and fgrep are considered obsolete. (PR #1509, thanks to David Seifert)

  • Switch to building libdefalte with cmake for Cirris CI. (PR #1511)

  • Ensure strings in config_vars.h are escaped correctly. (PR #1530, fixes #1527. Reported by Lucas Czech)

  • Easier modification of shared library permissions during install. (PR #1532, fixes #1525. Reported by StephDC)

  • Fix build on ancient compilers. Added -std=gnu90 to build tests so older C compilers will still be happy. (PR #1524, fixes #1523. Reported by Martin Jakt)

  • Switch MacOS CI tests to an ARM-based image. (PR #1536)

  • Cut down the number of embed_ref=2 tests that get run. (PR #1537)

  • Add symbol versions to libhts.so. This is to aid package developers. (PR #1560 addresses #1505, thanks to John Marshall. Reported by Stefan Bruens)

  • htscodecs now updated to v1.4.0. (PR #1563)

  • Cleaned up misleading system error reports in test_bgzf. (PR #1565)
    Bug fixes

Bug fixes

  • VCF. Fix n-squared complexity in sample line with many adjacent tabs [fuzz]. (PR #1503)

  • Improved bcftools detection and reporting of bgzf decode errors. (PR #1504, thanks to Lilian Janin. PR #1529 thanks to Bergur Ragnarsson, fixes #1528. PR #1554)

  • Prevent crash when the only FASTA entry has no sequence [fuzz]. (PR #1507)

  • Fixed typo in sam.h documentation. (PR #1512, thanks to kojix2)

  • Fix buffer read-overrun in bam_plp_insertion_mod. (PR #1520)

  • Fix hash keys being left behind by bcf_hdr_remove. (PR #1535, fixes #1533. Reported by Giulio Genovese in #842)

  • Make bcf_hdr_idinfo_exists more robust by checking id value exists. (PR #1544, fixes #1538. Reported by Giulio Genovese)

  • CRAM improvements. Fixed crash with multi-threaded CRAM. Fixed a bug in the codec parameter learning for CRAM 3.1 name tokeniser. Fixed Cram compression container substitution matrix generation, (PR #1558, PR #1559 and PR #1562)

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