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Eigenvector

nchernia edited this page Feb 24, 2017 · 2 revisions

The eigenvector can be used to delineate compartments in Hi-C data at coarse resolution; the sign of the eigenvector typically indicates the compartment. The eigenvector is the first principal component of the Pearson's matrix.

Usage

eigenvector <NONE/VC/VC_SQRT/KR> <hicFile(s)> <chr> <BP/FRAG> <binsize> [outfile]

Examples

java -jar juicer_tools.jar eigenvector KR HIC001.hic 1 BP 1000000

This will calculate the eigenvector of chromosome 1 with KR normalization at 1Mb resolution and print to standard out

java -jar juicer_tools.jar eigenvector VC HIC001.hic X BP 5000 eigen.txt

This will calculate the eigenvector of chromosome X with VC normalization at 5Kb resolution and print to eigen.txt.