Version 2.2.367

Download and installation

S. the Installation section below.

Documentation

• Reporting Engine
• Tables, Listings and Figures Library (TLF)
• OSPSuite-R
• OSP Suite R Utils (ospsuite.utils)

New features and improvements

New features

Note

Users can now check out Reporting Engine Test Reports and access a bunch of template workflows including their R code, models, data and corresponding reports.

• Demography task received significant updates:
  • The article for demography has been updated with more comprehensive examples using more representative virtual populations and illustrating the effects of population workflows and settings (#1095, #1102)
  • Categorical parameters, such as Gender, are now accounted for demography range plots and displayed as boxplots (#1088)
  • Demography plots can now display observed data (#535)
• Mass Balance task received significant updates:
  • A dedicated article for mass balance has been created in the documentation (#1118)
  • Mass balance plots can leverage user-defined settings from json files as illustrated in the mass balance article (#1118)
  • Normalized mass balance plots now use time-dependent cumulative drug mass for normalization (#1039, #1118)
• Qualification DDI plots received the following improvements
  • Delta symbol (δ) from Guest et al. formula is indicated in table caption (#1069)
  • Guest criterion (δ) can be tuned through the configuration plan (#789)
  • DDI plot format is quadratic by default (#1051)
• Formatting to word reports can translate additional html tags (#382)
• Goodness of Fit task leverages groupID from Output objects to group multiple outputs in same time profile and residual plots (#1188).
  groupID is also leveraged in the plots of residuals across the simulations (#1251).

Minor improvements and bug fixes

• Monte Carlo sampling in ratio comparison workflows is now centralized, performed in the PK parameter calculation step and significantly faster (#536, #1086).
• Wording for ratio comparison workflow figures and tables has been updated (#1087)
• Number of bins in demography and PK parameter range plots is consistent with input (#1128)
• Link/bookmark targets in word reports are better placed (#1084)
• Qualification time profiles work when no observed data is contained (#1082)
• Qualification PKRatio uses ml/min/kg as default clearance - CL - unit (#1242)
• Static images in qualification reports are better handled (#955, #1071)
• Figure captions are displayed below the figure in the reports (#1053)
• Word report is updated if it already existed (#1055)
• LLOQ line is better displayed in the legend of time profile plots (#478)

Full Changelog: v2.1.244...v2.2.367

Installation

1. Prerequisites

• Install required packages from CRAN and from GitHub as described here.
• [OPTIONAL] Install Pandoc and SVG-Converter (required only for generation of reports in MS-Word format) as described here

2. Package installation

Finally, install the OSPSuite.ReportingEngine package:

• Package download (.tar.gz)
• Package download (.zip)